PKTX 10-K & 10-Q changes, risk factors and insider trading
ProtoKinetix, Inc. · Pharmaceutical Preparations · CIK 1128189 · All filings on SEC.gov
At a glance
What changed in the latest 10-K
Risk Factors
Largest changes
Insiderssee in full comparisoncontinue to have substantialcontrol over the Company. As ofMarchSeptember28,3,2025,2026, the Company’s directors and executive officers hold the current right to vote approximately34.3%7.83% of the Company’s outstanding votingstock; of which 28.8% is owned or controlled, directly or indirectly by the Company CEO, Clarence Smith.stock. In addition, the heir to the deceased CEO’s estate holds approximately 35.8% of outstanding voting stock. The Company’s directors and executive officers have the right to acquire additional shares which could increase their voting percentage significantly. As a result,Mr. Smith acting alone, and/ormany of these individuals acting together, may have the ability to exert significant control over the Company’s decisions and control the management and affairs of the Company, and also to determine the outcome of matters submitted to stockholders for approval, including the election and removal of a director, the removal of any officer and any merger, consolidation or sale of all or substantially all of the Company’s assets. Accordingly,Accordingly,this concentration of ownership may harm a future market price of the Company’s common stock by:
The Company may not be able to continue as a going concern. Our independent public accountants noted that our recurring losses from operations (see in full comparison$364,188$393,650 and$415,479$364,188 for the years ended December 31,20242025 and2023,2024, respectively) and negative net operating cash flow($223,050$135,377 and$375,989$223,050 for the years ended December 31,20242025 and2023,2024, respectively) raise substantial doubt about our ability to continue as a going concern. This may hinder our future ability to obtain financing or may force us to obtain financing on less favorable terms than would otherwise be available.
Full comparison: every changed paragraph (2)
Insiders continue to have substantial
control over the Company.
As of MarchSeptember 28,3, 2025,2026, the Company’s directors and executive
officers hold the current right
to vote approximately 34.3%7.83% of the Company’s outstanding voting stock; of which 28.8% is owned or controlled, directly or indirectly
by the Company CEO, Clarence Smith.stock. In addition, the heir to
the deceased CEO’s estate holds approximately 35.8% of outstanding voting stock. The Company’s directors and executive officers have the right to
acquire additional
shares which could increase their voting percentage significantly. As a result, Mr. Smith acting alone, and/or many of these individuals
acting together,
may have the ability to exert significant control over the Company’s decisions and control the management and affairs
of the Company,
and also to determine the outcome of matters submitted to stockholders for approval, including the election and removal
of a director,
the removal of any officer and any merger, consolidation or sale of all or substantially all of the Company’s assets. Accordingly,
Accordingly, this concentration of ownership may harm a future market price of the Company’s common stock by:
The Company may not be able to continue
as a going concern. Our independent public accountants noted that our recurring losses
from operations ($364,188$393,650 and $415,479
$364,188 for the years ended December 31, 20242025 and 2023,2024, respectively) and negative net operating cash flow ($223,050
$135,377 and $375,989$223,050 for the years
ended December 31, 20242025 and 2023,2024, respectively) raise substantial doubt about our ability to continue
as a going concern. This may hinder
our future ability to obtain financing or may force us to obtain financing on less favorable terms
than would otherwise be available.
Management's Discussion & Analysis (MD&A)
Largest changes
During the year ended December 31,see in full comparison2024,2025, net cashusedprovidedinby operating activities decreased$152,939by $87,673 from$375,989a use of $223,050 to$223,050$135,377 provided for the years ended December 31,20232024 and2024,2025, respectively. Thisdecreasechange was predominantly due tothe overall decreased spending on web marketing, news releases, and social media, as well as significant reductionincrease innewaccountsresearch spending. Informative updates have been posted on the Company website, reducing the need for news releases and associated expenses.payable.
During the year ended December 31,see in full comparison2024,2025, net cash provided by financing activitiesreduceddecreased by$174,000$58,500 from$430,000$256,000 to$256,000$197,500 for the years ended December 31,20232024 and20242025 respectively. This decrease was predominantly due to a reduction in funding of new research through private placement of common stock shares.
At December 31,see in full comparison2024,2025, we hada $4,697 shortfall$1,118 in cash andnegative $3,647$2,168 in total current assets. As of December 31,2024,2025, we had a negative working capital equity deficit position of$127,694.$183,266. Although as of the date of this Annual Report we do not believe we have sufficient capital to meet cash flow projections and carry forward our business objectives in the short-term, the Company will need additional working capital to continue its medical research or to be successful in any future business activities and continue to pay its liabilities. There can be no assurance that in the future we will be able to raise capital from outside sources in sufficient amounts to fund our business.
During the year ended December 31,see in full comparison2024,2025, net cash used in investing activities decreasedslightlyby$1,098$1,747 as we continue to maintain global patent applications. Current year spending was narrowed to maintenance of existing patent family. Net cash used for investing activities for the year ended December 31,20232024 was$59,153.$58,055. Net cash used for investing activities for the year ended December 31,20242025 was$58,055.$56,308.
Full comparison: every changed paragraph (4)
At December 31, 2024,2025, we had a $4,697 shortfall$1,118 in
cash and negative $3,647 $2,168
in total current assets. As of December 31, 2024,2025, we had a negative working capital equity deficit position
of $127,694.$183,266. Although
as of the date of this Annual Report we do not believe we have sufficient capital to meet cash flow projections
and carry forward our
business objectives in the short-term, the Company will need additional working capital to continue its medical
research or to be successful
in any future business activities and continue to pay its liabilities. There can be no assurance that
in the future we will be able
to raise capital from outside sources in sufficient amounts to fund our business.
During the year ended December 31, 2024,2025, net cash
usedprovided inby operating activities decreased $152,939by $87,673 from $375,989a use of $223,050 to $223,050$135,377 provided for the years ended December 31, 2023 2024
and 2024,2025, respectively.
This decreasechange was predominantly due to the overall decreased spending on web marketing, news releases, and social media, as well as significant
reductionincrease in newaccounts research spending. Informative updates have been posted on the Company website, reducing the need for news releases and
associated expenses.payable.
During the year ended December 31, 2024,2025, net cash
used in investing activities decreased slightly by $1,098$1,747 as we continue to maintain global patent applications. Current year spending
was narrowed
to maintenance of existing patent family. Net cash used for investing activities for the year ended December 31, 20232024 was
$59,153. $58,055.
Net cash used for investing activities for the year ended December 31, 20242025 was $58,055.$56,308.
During the year ended December 31, 2024,2025, net cash
provided by financing activities reduceddecreased by $174,000$58,500 from $430,000$256,000 to $256,000$197,500 for the years ended December 31, 20232024 and 20242025 respectively.
This decrease was predominantly due to a reduction in funding of new research through private placement of common stock shares.
What changed in the latest 10-Q
Risk Factors
As a “smaller reporting company” as defined by Item 10 of Regulation S-K, we are not required to provide information required by this Item. However, our current risk factors are set forth in our Annual Report on Form 10-K for the year ended December 31, 2024 as filed with the SEC on March 28, 2025.
No wording changes found in this section.
Full comparison: every changed paragraph (0)
Management's Discussion & Analysis (MD&A)
Largest changes
The Company’s net loss wassee in full comparison$188,757$273,663 for thethe six-monthnine-month period endedJuneSeptember 30, 2025 compared to$177,103$261,676 for thesix-monthnine-month period endedJuneSeptember 30, 2024. The expenses were primarily incurred for professional fees, consulting services related to the operations of the Company’s business, research and development and other general and administrative expenses. Significant changes from the priorsix-monthnine-month period endedJuneSeptember 30, 2025 include:
Net cash used in operating activitiessee in full comparisonremained flat, changingfell by$6,664$41,873 from$138,691$177,808 to$132,027$135,935 for thesix-monthsnine-months endedJuneSeptember 30, 2024, and 2025, respectively. With the year over year changechangeprimarily from a change in accounts payable.
Net cash provided by financing activities fell $38,500see in full comparison$87,500from$255,000$216,000 to$167,500$177,500 for thesix-monthsnine-months endedJuneSeptember 30, 2024, and 2025, respectively. The decrease of funding from private placementsplacementsthrough thefirstthirdhalfquarter of 2025 reflects investor support for our slowing of operations and focus on finding financial partners for further research and development.
Research and development expendituressee in full comparisonslightlyincreased year over year with a change of$583$3,768 from$57,625$78,625 to$58,208$82,393 as the Company paid for molecule storage and consultingfees.fees but has no current research projects underway. The company continues to pursue research partners for cost sharing and engages in institutes with grants available for continued studies on our patented AAGP molecule.
Net cash usedsee in full comparisoninfor investing activities was$30,664$36,261 for thesix-monthnine-month period endedJuneSeptember 30, 2025 while the Company had net cash usedinfor investing activities of$35,517$52,910 for the comparative period. The difference is attributable to a year-to-datedecreasefluctuation in patent application billings for current year.
“Share-based compensation was $Nil for current year compared to $1,354 for the nine months ended September 2024.”see in full comparison
Full comparison: every changed paragraph (12)
The following discussion provides information
regarding regarding
the results of operations for the six-monthnine-month period ended JuneSeptember 30, 2025 and 2024, and our financial condition, liquidity
and capital resources
as of JuneSeptember 30, 2025 and December 31, 2024. The financial statements and the notes thereto contain detailed
information that should
be referred to in conjunction with this discussion.
Finally, our future results will depend
upon upon
various other risks and uncertainties, including, but not limited to, those detailed in our filings with the SEC under the Exchange
Act Act
and the Securities Act, including our Annual Report on Form 10-K for the fiscal year ended December 31, 2024 and our Quarterly Report
on Form 10-Q for the period ended JuneSeptember 30, 2025. All forward-looking statements attributable to us or persons acting on our
behalf behalf
are expressly qualified in their entirety by the cautionary statements in this paragraph and elsewhere in this Quarterly Report.
Other Other
than as required under securities laws, we do not assume a duty to update these forward-looking statements, whether as a result
of new
information, subsequent events or circumstances, changes in expectations or otherwise
The Company’s net loss was $188,757$273,663 for
the the
six-monthnine-month period ended JuneSeptember 30, 2025 compared to $177,103$261,676 for the six-monthnine-month period ended JuneSeptember 30, 2024. The expenses
were primarily
incurred for professional fees, consulting services related to the operations of the Company’s business, research
and development
and other general and administrative expenses. Significant changes from the prior six-monthnine-month period ended June September
30, 2025 include:
Professional fees increased by $8,347$9,344 from $67,802$98,647
to $76,149$107,991 due to increases in auditing fees and legal billing associated with yearyear- end and interim reporting.
Research and development expenditures slightly increased
year over year with a change of $583$3,768 from $57,625$78,625 to $58,208$82,393 as the Company paid for molecule storage and consulting fees.fees but has no
current research projects underway. The company
continues to pursue research partners for cost sharing and engages in institutes with
grants available for continued studies on our patented
AAGP molecule.
Share-based compensation was $Nil for current year compared to $1,354 for the nine months ended September 2024.
The following summarizes our balance sheet at JuneSeptember 30, 2025 and
December December
31, 2024:
At JuneSeptember 30, 2025, we had $112$607 in cash and $1,162
$1,657 in
total current assets and a negative working capital equity position of $(147,922225,539). Based
upon our
working capital equity as of JuneSeptember 30, 2025, we will require additional equity and/or debt financing in order to meet cash
flow projections
and carry forward our business objectives.
Net cash used in operating activities remained flat,
changingfell by $6,664
$41,873 from $138,691$177,808 to $132,027$135,935 for the six-monthsnine-months ended JuneSeptember 30, 2024, and 2025, respectively. With the year over year change
change primarily from a change in accounts payable.
Net cash used infor investing activities was $30,664$36,261
for the six-monthnine-month period ended JuneSeptember 30, 2025 while the Company had net cash used infor investing activities of $35,517$52,910 for the comparative
period. The difference is attributable to a year-to-date decreasefluctuation in patent application billings for current year.
Net cash provided by financing activities fell
$38,500 $87,500
from $255,000$216,000 to $167,500$177,500 for the six-monthsnine-months ended JuneSeptember 30, 2024, and 2025, respectively. The decrease of funding from private
placements placements
through the firstthird halfquarter of 2025 reflects investor support for our slowing of operations and focus on finding financial partners
for further
research and development.
Although management expects that our operations
will will
be influenced by general economic conditions, we do not believe that inflation had a material effect on our results of operations
during during
the threenine months ended JuneSeptember 30, 2025.
PKTX insider buying and selling (Form 4)
Since 2026-04-11, insiders reported open-market purchases in 0 Form 4 filings and open-market sales in 0 filings. Totals add up every open-market (code P and S) line in those filings, using the prices reported in the filings. Awards, option exercises, tax withholding and gifts are listed below but not counted.
No Form 4 stock transactions in this period.
Well-known investors holding PKTX (13F)
None of the 59 investors we track reported a position in their latest 13F.